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Vaxil Bio Ltd V.VXL

Alternate Symbol(s):  VXLLF

Vaxil Bio Ltd. is a Canada-based biotechnology company. The Company is focused on a drug discovery and development platform based on Signal Peptides (SPs) which the Company deploys to fight infectious diseases and cancer. The Company’s most advanced product, ImMucin, a MUC1 SP-derived vaccine, completed a Phase I/II clinical trial in multiple myeloma. The Company also has a SP-based COVID-19 vaccine candidate and a SP-based tuberculosis vaccine / treatment candidate. In addition, The Company has mAb candidates for the treatment of oncology and infectious diseases to be used alone, and in combination with other treatments. It has also initiated a pre-clinical program for a drug delivery polymer that targets high affinity E-selectin (P-Esbp), which the Company licensed for development and commercialization from BGN Technologies. It exploits the properties of SP domains on crucial proteins to develop targeted therapies against cancer targets and infectious disease pathogens.


TSXV:VXL - Post by User

Bullboard Posts
Post by ISRAELon Mar 20, 2020 12:12pm
512 Views
Post# 30830780

🇮🇱Crash Spilled Tardigrades on Moonℹ

🇮🇱Crash Spilled Tardigrades on MoonℹAlien Viruses
IT WAS JUST before midnight on April 11 and everyone at the Israel Aerospace Industries mission control center in Yehud, Israel, had their eyes fixed on two large projector screens. On the left screen was a stream of data being sent back to Earth by Beresheet, its lunar lander, which was about to become thefirst private spacecraft to land on the moon. The right screen featured a crude animation of Beresheet firing its engines as it prepared for a soft landing in the Sea of Serenity. But only seconds before the scheduled landing, the numbers on the left screen stopped. Mission control had lost contact with the spacecraft, and it crashed into the moon shortly thereafter.
 
Half a world away, Nova Spivack watched a livestream of Beresheet’s mission control from a conference room in Los Angeles. As the founder of the Arch Mission Foundation, a nonprofit whose goal is to create “a backup of planet Earth,” Spivack had a lot at stake in the Beresheet mission. The spacecraft was carrying the foundation’s first lunar library, a DVD-sized archive containing 30 million pages of information, human DNA samples, and thousands of tardigrades, those microscopic “water bears” that can survive pretty much any environment—including space.
 
But when the Israelis confirmed Beresheet had been destroyed, Spivack was faced with a distressing question: Did he just smear the toughest animal in the known universe across the surface of the moon?
 
In the weeks following the Beresheet crash, Spivack pulled together the Arch Mission Foundation’s advisers in an attempt to determine whether the lunar library had survived the crash. Based on their analysis of the spacecraft’s trajectory and the composition of the lunar library, Spivack says he is quite confident that the library—a roughly DVD-sized object made of thin sheets of nickel—survived the crash mostly or entirely intact. In fact, the decision to include DNA samples and tardigrades in the lunar library may have been key to its survival.
 
“For the first 24 hours we were just in shock,” Spivack says. “We sort of expected that it would be successful. We knew there were risks but we didn’t think the risks were that significant.”
 
The promising thing about the tardigrades, says Spivack, is that they could hypothetically be revived in the future. Tardigrades are known to enter dormant states in which all metabolic processes stop and the water in their cells is replaced by a protein that effectively turns the cells into glass. Scientists have revived tardigrades that have spent up to 10 years in this dehydrated state, although in some cases they may be able to survive much longer without water. Although the lunar library is designed to last for millions of years, scientists are just beginning to understand how tardigrades manage to survive in so many unforgiving environments. It’s conceivable that as we learn more about tardigrades, we’ll discover ways to rehydrate them after much longer periods of dormancy.

Creating a backup of the entire planet is the sort of high-minded idealism associated with the titans of Silicon Valley, but Spivack is well on his way to turning it into a reality. And as the world grapples with the fallout from climate change, the prospect of nuclear war, and even killer asteroids, creating a backup of human civilization doesn’t sound like such a bad idea after all.
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