Antibe Therapeutics Inc(Pre-Merger) ATBPF

Healthcare Biotechnology

Antibe Therapeutics Inc. is a clinical-stage biotechnology company. The Company is leveraging its hydrogen sulfide (H2S) platform to develop therapies to target inflammation arising from a range of medical conditions. The Company’s pipeline includes assets that seek to overcome the gastrointestinal ulcers and bleeding associated with nonsteroidal anti-inflammatory drugs (NSAIDs). Its lead drug, otenaproxesul, is in clinical development as an alternative to opioids and NSAIDs for acute pain. Its second pipeline drug, ATB-352, is being developed for a specialized pain indication. The Company also focuses on inflammatory bowel disease (IBD). Otenaproxesul combines a moiety that releases hydrogen sulfide with naproxen, a non-steroidal, anti-inflammatory drug. ATB-352 is an H2S-releasing derivative of ketoprofen, a potent NSAID commonly prescribed for acute pain. Its IBD candidates are being designed to maintain the efficacy, safety, and pharmacokinetic properties of ATB-429.

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Antibe Therapeutics Inc(Pre-Merger)

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Comment by bringon10baggeron Mar 31, 2020 2:00pm

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Post# 30865104

RE:RE:RE:RE:Patience will pay off...

They also concluded that an increase in dosage reacted exponetially and not linearily which led to finding the lowest dose with effective results, where we are today. Just think discussions with FDA and big pharma on partnering would not take place if they weren't confident in the results. Whether it be 200mg or 250mg results will be effective and will solidify it being the "game changing NSAID.of the future....... t

MUGMODs wrote: Oh no problem - just didn't want others using it as a scare tactic here.

In Phase One ... if I have it right (I came after the share price fall), there was one person in the trial who had Hep C but didn't disclose. So, when that person ended up sick, the trial was in trouble.

Also, another scare came from high levels of toxicity.

Some thought the journey had come to an end ... but ... once the figured out the Hep C issue and once they figured out they were using too much of the drug (at 250 mg - twice daily ???) then everything came in line. That's the way I remember it ... could be off a bit.

I hope that helps. Let me know if you need any clarification.