RE:RE:RE:RE:RE:New Paper on TLD-1433 and Lung Cancer
vestor111 wrote: WOW! WOW! WOW! Incredible find Eogan! Just catching up.
I believe the therapy being proposed is a topical application which may mean it is already covered by the NMIBC Ph1b trial. (GBM would probably require an IV instillation and may require it's own Ph1b.)
If this assumption is correct about being a topical application and covered already by the Ph1b trial for NMIBC...a NSCLC trial could progress fairly rapidly and it sound like it might be a very low cost to pursue.
This could be quite huge - fast to trial and low cost to execute with a knowledgeable and willing US partner.
This is huge Vestor...& the plan IS to instill a saline solution of TLD-1433 directly into the thoracic cavity. I agree...the similar drug delivery has the potential to significantly expedite an NSCLC trial by accelerating a Ph 1 or possibly skipping it altogether, especially if TLD dosage & laser frequency are ultimately similar to those used in NMIBC. Not sure if the different indication makes a significant difference here, but that's what a pre-IND consultation is for. Good luck...