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Ibio Inc IBIO

iBio, Inc. is a preclinical stage biotechnology company that leverages artificial intelligence (AI) for the development of precision antibodies. The Company develops biopharmaceuticals using computational biology and 3D-modeling of subdominant and conformational epitopes, prospectively enabling the discovery of new antibody treatments for hard-to-target cancers and other diseases. Its StableHu technology is an AI-based tool designed to predict a library of antibodies with fully human Complementarity-Determining Region (CDR) variants based on an input antibody. Its pre-clinical pipeline of immuno-oncology targets the treatment of solid tumors, glioblastoma, head, and neck cancers. Its pipeline includes IBIO-101, TROP-2 x CD3, MUC16, EGFRvIII, CCR8, and Target 5. IBIO-101 is an anti-CD25 monoclonal antibody (mAb) that has demonstrated in preclinical models of disease the ability to bind and deplete immunosuppressive regulatory T (Treg) cells to inhibit the growth of solid tumors.


NYSEAM:IBIO - Post by User

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Post by FelixFunon Aug 31, 2020 7:44am
320 Views
Post# 31478174

iBio Inc – A Key COVID-19 Vaccine Player

iBio Inc – A Key COVID-19 Vaccine PlayerWhile other coronavirus stocks have been making big moves in April, iBio Stock (NYSEAMERICAN:IBIO) has been stuck trading just under the $1 level. With Aytu Bioscience Inc, Inovio Pharmaceuticals, and Moderna Inc having just made huge moves, IBIO stock looks to be the next coronavirus play to make a big move.

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“We are excited to be a partner in the development of IBIO-200. Combining iBio’s VLP antigen with an IDRI adjuvant provides for promising safety and efficacy characteristics, and importantly, the ready ability to scale-up manufacturing to help meet the projected global demand for a suitable vaccine.”

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But because of all the funding that BARDA had done, I had said ,“hey, do you have any ideas on people that you have worked with? Or are there any interesting adjuvants out there because we’d like to perform this study?” And so, they recommended that we reach out to folks at the Infectious Disease Research Institute in Seattle. And the next day we did, and I thankfully, Dr Corey Casper there — a brilliant scientist and leader in the field — took our call, and then, you know, we’ve been working with them since and the great part was, they had these wonderful adjuvant technologies and tremendous clinical experience, clinical development experience. So, two great things. We’re thankful to BARDA for recommending that, thankful to the folks at IDRI they’re called, that’s the acronym. And then also, too, is we’re trying to get ready for hopefully moving into human clinical trials. We had the folks at IBM also with their clinical trials management software. They said,“Hey, we kind of like what you’re doing” And they’ve given us a little bit of help there in that regard, too. So, you know, really, really thankful to the U. S. government and BARDA in particular for that marriage that they helped make.

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“That scalability links directly to the modular technology behind our FastPharming Manufacturing System, which uses a relative of the tobacco plant as the ‘bioreactor’ to produce biopharmaceuticals. So, the amount of product generated by a single plant is consistent from research- to commercial-scale, and scale-up is achieved by simply growing thousands more plants within our 130,000 square foot facility.  This is real innovation in the manufacture of biopharmaceuticals, thus our significant synergy with the NIIMBL community.”

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