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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Healthcare Biotechnology
Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy. Its portfolio includes Phase I clinical trial of sudocetaxel zendusortide (TH1902), a novel peptide-drug conjugate (PDC), in patients with advanced ovarian cancer.


TSX:TH - Post by User

Theratechnologies Inc
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Comment by JayjayUSA12007on Sep 19, 2020 9:28pm
190 Views
Post# 31587930

RE:RE:RE:RE:RE:RE:RE:RE:Ibalizumab paper

RE:RE:RE:RE:RE:RE:RE:RE:Ibalizumab paperQuote:"...I guess they had concerns the drug wouldn't cross the blood brain barrier and therefore virus in the csf could escape the drug and replicate.
What they found was viral loads were low similar to the levels seen in the blood after treatment started..."

So, in other words, the study confirmed that Trogarzo did cross the blood brain barrier and did have the same effect in the CSF as well as in patients' blood stream. Without this capability, Trogarzo efficacy would have been short termed. In addition, since they found no evidence of HIV virus mutation, Trogarzo efficacy would have longer lasting impact than previously known.
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