Sherri's patentThis is the patent Sherri has for dental application - I don't believe Theralase has an attachment.
The present invention describes extracts of Polygonum cuspidatum and related compositions that are capable of photodynamic inactivation (PDI) of microorganisms such as bacteria, viruses, fungi, and protozoa, and capable of killing or inactivating cancer cells. The present invention further describes methods of using said Polygonum cuspidatum extracts and photodynamic inactivation (PDI) as a therapy for the treatment of microbial infection and as well as the use of Polygonum cuspidatum extract and related compositions as photodynamic therapy agents for the treatment of cancer.
SUMMARY OF THE INVENTION
In one aspect, the present invention relates to a method of killing or inactivating microorganisms, the method comprising the steps of contacting the microorganisms with a composition comprising an extract of Polygonum cuspidatum and an excipient; and irradiating the microorganisms with a source of light. In one embodiment, the method is performed in the presence of oxygen. In one embodiment, the microorganisms are in the oral cavity of a subject. In one embodiment, the microorganisms are part of a biofilm. In one embodiment, the microorganisms are attached to a dental appliance. In one embodiment, the dental appliance is selected from the group consisting of orthodontic brackets, bands, buttons, bonded attachments, bonded wire, crowns, inlays, onlays, restorations, dental abutments, and dental implants. In one embodiment, the microorganisms are selected from the group consisting of as bacteria, viruses, fungi, and protozoa. In one embodiment, the microorganisms are on the surface of a tooth, in the a cavity in a tooth, on the surface of the gums, or on the mandibular or maxillary arches.
16/264,737 | Polygonum Cuspidatum Extracts As Photodynamic Inactivating Agents | 206204-0001-01US | | | |
Date | Transaction Description | 10-16-2020 | Notice of Allowance Data Verification Completed | 10-14-2020 | Examiner's Amendment Communication | 10-13-2020 | Interview Summary - Applicant Initiated - Telephonic | |