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Sernova Corp T.SVA

Alternate Symbol(s):  SEOVF

Sernova Corp. is a Canada-based clinical-stage biotechnology company, which is developing therapeutic cell technologies for chronic diseases, including insulin-dependent diabetes, thyroid disease, and blood disorders that include hemophilia A. The Company is focused on developing a functional cure for insulin-dependent diabetes with its therapeutic cell technology, the Cell Pouch System, a novel implantable and scalable medical device with immune protected therapeutic cells. The Cell Pouch is a scalable, implantable medical device. The Cell Pouch is designed to create a vascularized organ-like environment for the transplantation and engraftment of therapeutic cells. Its regenerative medicine therapeutic approach is to provide cell therapies where the cells, transplanted within an organ-like vascularized implantable device, the Cell Pouch, generates proteins, hormones or factors released into the bloodstream for treatment of diseases requiring replacement of these molecules in the body.


TSX:SVA - Post by User

Comment by jwalliscaon Nov 30, 2020 9:34am
82 Views
Post# 31999368

RE:RE:RE:RE:C-Peptide, why the body likes it :)

RE:RE:RE:RE:C-Peptide, why the body likes it :)S7:

Your question is effectively answered in the vernacular by what you wrote.

Today's news is effectively on this subject and will be released in a detailed Scientific manner by Dr. Witkowski in Jan 2021.

I have no idea why Stockhouse's "post a link" didn't work in a previous post... Attempt #2 with a different method.

Mon Nov 30th, 2020


LONDON, ONTARIO - TheNewswire - November 30, 2020 - Sernova Corp. (TSXV:SVA) (OTC:SEOVF (FSE:PSH), a leading clinical-stage regenerative medicine therapeutics company, is pleased to announce that Dr. Piotr Witkowski, principal investigator in Sernova's ongoing Phase I/II clinical trial, A Safety, Tolerability and Efficacy Study of Sernova's Cell Pouch(TM) for Clinical Islet Transplantation will present data and observations from the trial in an oral presentation delivered at the American Society of Transplant Surgeons 21 st Annual State of the Art Winter Symposium.

Dr. Witkowski, Director, Pancreatic and Islet Transplant Program at the University of Chicago, is scheduled to deliver his presentation, Islet Allotransplantation Into Pre-Vascularized Sernova Cell Pouch (TM) - Preliminary Results From The University of Chicago, to more than 600 transplant professionals as part of the Oral Abstract Session II on January 15, 2021 at 2:05 PM. Further details on the program and registration can be found on ASTS Winter Symposium website ( https://asts.org/events-meetings/winter-symposium )

ABOUT ASTS AND THE 21 st ANNUAL STATE OF THE ART WINTER SYMPOSIUM

The American Society of Transplant Surgeons represents approximately 1,900 professionals dedicated to excellence in transplantation surgery. ASTS advances the art and science of transplant surgery through patient care, research, education, and advocacy.

ASTS 21st Annual State of the Art Winter Symposium will be held virtually January 14 - 16, 2021.

Beginning on January 14, the sessions will be available virtually to disseminate the latest science in transplantation surgery.

ABOUT SERNOVA'S CLINICAL TRIAL

Sernova is conducting a Phase I/II non-randomized, unblinded, single-arm, company-sponsored trial to assess the safety and tolerability of islet transplantation into the company's patented Cell Pouch in diabetic subjects with hypoglycemia unawareness. The primary objective of the study is to assess the safety of the Cell Pouch following implantation and transplantation. The secondary objective is to assess efficacy through a series of defined measures. Patients enrolled in Sernova's clinical trial are incapable of producing C-peptide, a biomarker for insulin produced by islet cells.

Eligible subjects are implanted with Cell Pouches. Following the development of vascularized tissue chambers within the Cell Pouch, subjects are then stabilized on immunosuppression, and a dose of purified islets, under strict release criteria, is transplanted into the Cell Pouch.

A sentinel pouch is removed for an early assessment of the islet transplant. Subjects are followed for additional safety and efficacy measures for approximately six months. At this point, a decision will be made with regards to the transplant of a second islet dose with subsequent safety and efficacy follow-up. Patients will be then further followed for one year to assess longer-term safety and efficacy.

For more information on the clinical trial, please visit www.clinicaltrials.gov/ct2/show/NCT03513939 .

For more information on enrollment and recruitment details please visit www.pwitkowski.org/sernova .

ABOUT SERNOVA CORP.

Sernova Corp is developing regenerative medicine therapeutic technologies using a medical device and immune protected therapeutic cells (i.e. human donor cells, corrected human cells, and stem cell-derived cells) to improve the treatment and quality of life of people with chronic metabolic diseases such as insulin-dependent diabetes, blood disorders including hemophilia, and other diseases treated through replacement of proteins or hormones missing or in short supply within the body. For more information, please visit www.sernova.com

For further information contact:

Dominic Gray

Sernova Corp

Tel: (519) 858-5126

dominic.gray@sernova.com

www.sernova.com


jwall
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