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Algernon Pharmaceuticals Inc. C.AGN

Alternate Symbol(s):  AGNPF

Algernon Pharmaceuticals Inc. is a clinical-stage drug development company. The Company is focused on developing repurposed therapeutic drugs in the areas of non-alcoholic steatohepatitis (NASH), a type of liver disease, chronic kidney disease (CKD), inflammatory bowel disease (IBD), idiopathic pulmonary fibrosis (IPF) and chronic cough as well as advancing a stroke program using N, N-Dimethyltryptamine (DMT). The Company operates through two segments, which includes the development of repurposed therapeutic drugs in Canada and the facilitation of the Company’s lead drug candidates into off-label phase II clinical trials (humans) in Australia. The Company's pipeline includes NP-251 (Repirinast) and AP-188 (DMT). The Company, through its subsidiary, Algernon NeuroScience Inc., is developing AP-188 (DMT) as a potential treatment for stroke and traumatic brain injury (TBI) recovery. Its NP-251 is being developed as a potential treatment for kidney inflammation and fibrosis.


CSE:AGN - Post by User

Comment by Biofinanaceon Dec 11, 2020 6:22pm
205 Views
Post# 32091315

RE:RE:Thank you

RE:RE:Thank youI will be more than happy to see such multipliers. 

Just to correct - So far AGN is running 2 clinical trials 
1) COVID - https://clinicaltrials.gov/ct2/show/NCT04382924?term=algernon&draw=2&rank=1
2) IPF & its assoicated cough - https://clinicaltrials.gov/ct2/show/NCT04318704?term=algernon&draw=2&rank=2

AGN has NO clinical trial for chronic cough alone as an indication. But fixing cough in IPF patients will be a multi billion $$ feast. No companies have shown any relief in cough in IPF patients. These patients cough 200-250 times a day (which is 2-3x than normal chronic cough patients). 

Merck Gefapixant (which is in Ph3-registrational for chronic cough and could be a block buster drug) failed to show relief in IPF related cough. 

IPF cough is the worst thing to fix coz many patients lung injury is so severe that in many cases they are missing part of their lung. Like I said some physician prescribe them Ninetadinib or Perfenidone for IPF cough. 

But the moment AGN initiates a trial in CHronic cough or NASH then valuation will be even harder to perform.

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