Antibe Therapeutics Inc(Pre-Merger) ATBPF

Healthcare

Antibe Therapeutics Inc. is a clinical-stage biotechnology company. The Company is leveraging its hydrogen sulfide (H2S) platform to develop therapies to target inflammation arising from a range of medical conditions. The Company’s pipeline includes assets that seek to overcome the gastrointestinal ulcers and bleeding associated with nonsteroidal anti-inflammatory drugs (NSAIDs). Its lead drug, otenaproxesul, is in clinical development as an alternative to opioids and NSAIDs for acute pain. Its second pipeline drug, ATB-352, is being developed for a specialized pain indication. The Company also focuses on inflammatory bowel disease (IBD). Otenaproxesul combines a moiety that releases hydrogen sulfide with naproxen, a non-steroidal, anti-inflammatory drug. ATB-352 is an H2S-releasing derivative of ketoprofen, a potent NSAID commonly prescribed for acute pain. Its IBD candidates are being designed to maintain the efficacy, safety, and pharmacokinetic properties of ATB-429.

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Antibe Therapeutics Inc(Pre-Merger) > Checking up on Dr. J B Matson's research site ... what's new

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Post by MrMugsyon Dec 15, 2020 12:09pm

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Post# 32109249

Checking up on Dr. J B Matson's research site ... what's new

Further investigating Dr. John B Matson for updates.
Didn't realize the work also being done in COS ... newly added ... or me just not paying attention. Possibly the latter.
COS = Carbonyl Sulphide

More on COS ...
https://www.liebertpub.com/doi/10.1089/ars.2017.7119

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WELCOME to the Matson group website. We develop new small molecules and materials for biology, medicine, and sustainability using techniques and tools from organic chemistry, polymer chemistry, and supramolecular chemistry. Our research group is interdisciplinary, using chemistry to answer biological questions, discover potential new therapeutics, explore new polymer topologies, and design sustainable materials for a broad variety of applications. Current areas of focus include:

New compounds and materials for gasotransmitter delivery, focused on H2S and COS
Photo- and biodegradable polymer synthesis
Peptide-based responsive materials
New methods for synthesis of bottlebrush polymers
Novel covalent nanostructures with anisotropic shapes