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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy. Its portfolio includes Phase I clinical trial of sudocetaxel zendusortide (TH1902), a novel peptide-drug conjugate (PDC), in patients with advanced ovarian cancer.


TSX:TH - Post by User

Comment by canadapieton Jan 20, 2021 4:13pm
133 Views
Post# 32336401

RE:RE:RE:Phone call Mrs. Leah

RE:RE:RE:Phone call Mrs. LeahSorry and thx for the correction, but was writing in a hurry! And actually
i ment  NBE Therapeutics (Suisse) who were in fase 1 (i think) and were
bought by Boeringher Ingelheim.
(velosbio was bought by Merck for 2,75 B in cash).





qwerty22
 - (1/20/2021 1:57:47 PM) 
RE:RE:Phone call Mrs. Leah

Canadapiet I just want to correct you on one things. Velosbio is not a preclinical company. They were bought Nov2020 and Oct2020 they started their Ph2. So the price tag is for a company that has basically finished the clinical trial THTX is just about to start. They have their dose, their initial safety data and their initial efficacy data. The data set is small but strong

https://www.merck.com/news/merck-to-acquire-velosbio/

They are also developing a bi-specific antibody based on their IP. That's another very hot sector of cancer drug development. Essentially you have one antibody that targets T-cells and one that targets cancer cells that are joined together and so you force the two cell types to come together and get the T-cells to do their thing without first having to develop a cancer specific response. I don't know if it's possible but it wouldn't be a terrible thing for THTX to explore an antibody/peptide conjugate that did the same thing targeting sortilin. I might believe they were an ideas machine if they did something like that.

 

 


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