GREY:ATBPF - Post by User
Comment by
MrMugsyon Jan 25, 2021 1:45am
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Post# 32373090
RE:Old IBD patents ...
RE:Old IBD patents ...MrMugsy wrote: They were also for prevention/treatment of colon cancer.
Assuming the same opportunity exists for the new molecule - would just be for a future indication.
Walk before we run ?
Derivatives of 4- or 5-aminosalicylic acid Abstract The present invention provides new derivatives of 4- or 5-aminosalicylic acid, and a pharmaceutical composition containing these derivatives of 4- or 5-aminosalicylic acid as active ingredients, useful for the treatment of intestinal diseases such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) and for the prevention/treatment of colon cancer. More particularly, these derivatives comprise a hydrogen sulfide releasing moiety linked via an azo, an ester, an anhydride, a thioester or an amide linkage to a molecule of 4- or 5-aminosalicylic acid. Furthermore, the present invention provides a process for preparing these compounds and their use for treating IBD and IBS and the prevention/treatment of colon cancer.
Guess Google helped me confirm ...
Together, IBD is estimated to affect more than 0.4% of Europeans and North Americans, a number that is expected to increase over time[1]. It is well recognized that patients with IBD are at an increased risk of developing colorectal cancer (CRC), primarily the result of chronic intestinal inflammation https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873872/#:~:text=Together%2C%20IBD%20is%20estimated%20to,inflammation%5B2%2D4%5D.