Institution Review Boards (IRB's)Have been trying to understand different IRB levels ... 'central IRB' versus 'local IRB' as contained in TLT first (Jan.19) release on US sites, and found this IRB FAQ page on the FDA's site. I still don't know who exactly is the 'central IRB' in this case and what breadth they have across the US (is it regional or does it include entire US?) but still found the FAQ's to be very interesting.
https://www.fda.gov/regulatory-information/search-fda-guidance-documents/institutional-review-boards-frequently-asked-questions