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Antibe Therapeutics Inc(Pre-Merger) ATBPF

Antibe Therapeutics Inc. is a clinical-stage biotechnology company. The Company is leveraging its hydrogen sulfide (H2S) platform to develop therapies to target inflammation arising from a range of medical conditions. The Company’s pipeline includes assets that seek to overcome the gastrointestinal ulcers and bleeding associated with nonsteroidal anti-inflammatory drugs (NSAIDs). Its lead drug, otenaproxesul, is in clinical development as an alternative to opioids and NSAIDs for acute pain. Its second pipeline drug, ATB-352, is being developed for a specialized pain indication. The Company also focuses on inflammatory bowel disease (IBD). Otenaproxesul combines a moiety that releases hydrogen sulfide with naproxen, a non-steroidal, anti-inflammatory drug. ATB-352 is an H2S-releasing derivative of ketoprofen, a potent NSAID commonly prescribed for acute pain. Its IBD candidates are being designed to maintain the efficacy, safety, and pharmacokinetic properties of ATB-429.


GREY:ATBPF - Post by User

Post by Duster340on Jan 30, 2021 11:31pm
411 Views
Post# 32430336

Echelon $15 price target

Echelon $15 price target

Echelon starts Antibe Therapeutics at speculative buy; PT $15 (Canadian)

Antibe Therapeutics

Echelon Capital Markets initiated coverage of Antibe Therapeutics (TSX:ATE) with a “speculative buy” rating and price target of $15 (Canadian). The stock was quoted at $3.70 in afternoon trading on Jan. 29.

Antibe is developing drugs for pain and inflammation that have improved side-effect profiles based on the company’s platform of hydrogen sulfide-releasing (H2S) analogs. Its lead drug, otenaproxesul, is an H2S-releasing analog of naproxen, a widely used non-steroidal anti-inflammatory drug that causes significant gastrointestinal side effects.

“Otenaproxesul has demonstrated strong efficacy and limited GI side effects in Phase 2b trials with osteoarthritis patients, which position it as a potential blockbuster treatment,” writes analyst Stefan Quenneville.

Mr. Quenneville said Antibe is currently engaged in partnership discussions for the commercialization rights to otenaproxesul for major markets, including the U.S., Europe and Japan. “We anticipate a deal with a Big Pharma partner in the next year, which should be a meaningful catalyst for the stock,” he added.

“While we are bullish on otenaproxesul’s clinical success, the key risks center on Phase 3 results that will only read out in 2023, proving an attractive entry point for investors in the interim,” Mr. Quenneville said.


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