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For the most part, psilocybin therapy studies have relied on self-reports from patients. However, in a study published in 2017, a group of researchers probed deeper into the mechanisms behind psilocybin and how it affects patients with treatment-resistant depression.
The researchers used MRI technology to scan cerebral blood flow and brain activity before and after taking psilocybin. Following the treatment, all patientssaw a decrease in their depressive symptoms after one week, and nearly half of them experienced the decrease last for at least five weeks. Check disclaimer on profile and landing page.