Number of USIn a number of U.S. cities and one state, psychedelics have only recently been legalized, placing it well behind cannabis, which is now available in some form in 35 states and is theoretically tracking federal legalization under President-elect Joe Biden. In November's election, Denver and Oakland also legalized psilocybin and Washington, D.C. fully legal mushrooms and other plant-based substances such as mescaline and ibogaine in 2019.