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Satellos Bioscience Inc ICOTF


Primary Symbol: T.MSCL Alternate Symbol(s):  MSCLF

Satellos Bioscience Inc. is a Canada-based a drug discovery and development company with a focus on muscle regeneration. The Company is focused on developing medicines to treat degenerative muscle conditions. Its MyoReGenX platform is specifically designed to recreate the specialized muscle stem cell niche in vitro. MyoReGenX platform enables to map pathways which modulate muscle repair and regeneration, identify, and confirm drug targets, and test drug candidates for their ability to restore muscle stem cell repair mechanisms that have been impaired by genetic mutations, disease or injury. Its lead program is an oral, small molecule drug candidate in development as a disease-modifying treatment for Duchenne muscular dystrophy. Its iCo portfolio includes Oral Amp B Delivery System, a patented oral transport technology and Bertilimumab a human monoclonal eotaxin antibody with potential to treat a range of allergic and inflammatory conditions mediated by eotaxin-1.


TSX:MSCL - Post by User

Post by db2067on Feb 25, 2021 9:41am
174 Views
Post# 32656666

QUICK SUMMARY

QUICK SUMMARYQUICK SUMMARY It all adds up for me, just a waiting game now for big news - market cap is so low here compared to equivalent peers that a balance-up share price to $0.25 - $0.30 makes sense see:

"Adalimumab (Humira) sells about $14 Billion / year in the US alone. Our Bertilimumab was developed by the same Nobel Winning Scientists at Cambridge Antibody that developed Humira. Our Bert has successfully passed Phase I and Phase II Trials in Bullous Pemphigoid and had FDA Orphan Drug and Fast Track Status." User ID: Rootbound

Co-008 and iCo Amp B have huge potential The joint development with Skymount is big with their access to Deep Drug AI iCo Therapeutics Announces Joint Development of iCo-019 with Skymount Medical https://www.newsfilecorp.com/release/71207/iCo-Therapeutics-Announces-Joint-Development-of-iCo019-with-Skymount-Medical

https://www.lsu.edu/research/news/2020/0605-deepdrug.php “DeepDrug has the power to perform 15 years of drug discovery and due diligence in 15 days and leads the pack in medical AI in terms of accuracy, speed, and performance.”—Zubin Kothawala, Skymount Medical

https://skymountmed.com/deep-drug/
https://skymountmed.com/covid/

Comapre the teams
https://skymountmed.com/about/ https://icotherapeutics.website/our-team/

Dr. Kishor Wasan and Dr. Peter Hnik on both - kind of a big deal. Both of iCo's drugs look pretty good to me, it has been a long time coming... plus a covid opportunity as well

iCo-008
Fast Track designation was recently granted for iCo-008 use in bullous pemphigoid (BP) by the US Food and Drug Administration (FDA). The FDA has also recently granted orphan drug designation to iCo-008 for the treatment of bullous pemphigoid.

iCo Amp B
Amphotericin B (Amp B) has been a gold standard for highly efficacious treatment of systemic fungal and parasitic infections with more than a 50-year history of intravenous (IV) formulations, yet no oral formulations are currently commercially available. The oral Amp B formulation developed by iCo Therapeutics may have significant advantages over an IV formulation with fewer adverse events and an easier way of administration. Assuming that clinical studies will confirm good safety and efficacy results, the oral Amphotericin B could be used in a variety of indications, including prevention of fungal infections in immunocompromised patients.

Historically, the main advantage of Amp B has been lower frequency of interaction with other drugs and a chance of developing drug-resistance to fungal infections. The early stages of the oral iCo Amp B program involved various formulations of Amp B used in nonclinical models of aspergillosis and candidiasis as well as leishmaniasis. All studies showed good efficacy and safety of the oral Amp B formulations, and the compound selected for further clinical development in capsule form is referred to as iCo-019.



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