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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy. Its portfolio includes Phase I clinical trial of sudocetaxel zendusortide (TH1902), a novel peptide-drug conjugate (PDC), in patients with advanced ovarian cancer.


TSX:TH - Post by User

Post by scarlet1967on Mar 03, 2021 6:36pm
226 Views
Post# 32711217

Efficacy, pharmacokinetics, and safety of Trogarzo

Efficacy, pharmacokinetics, and safety of Trogarzo
Good to see more recognition of Trogarzo’s efficacy/safety on a well credited journal.
 
“In this highly treatment-experienced population, ibalizumab administered q2wk at 15 mg/kg or at 10 mg/kg (with weekly dosing during the 9-week loading period) was safe and well tolerated and resulted in sustained antiviral and immunological response over 48 weeks. With proven activity against multiple drug-resistant strains regardless of viral tropism, ibalizumab is a valuable addition to the treatment armamentarium. Because of its effective inhibition of HIV entry, tolerability, and long-acting dosing, ibalizumab is an attractive drug for use in individuals with limited treatment options because of multidrug resistance.”

https://journals.lww.com/jaids/Fulltext/2021/04010/Efficacy,_Pharmacokinetics,_and_Safety_Over_48.16.aspx
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