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StageZero Life Sciences Ltd T.SZLS

Alternate Symbol(s):  SZLSF

StageZero Life Sciences, Ltd. is a Canada-based vertically integrated healthcare company. The Company is engaged in improving the early detection and management of cancer and other chronic diseases through diagnostics and telehealth programs that provide clinical interventions to assist patients who have cancer (COC Protocol), and help patients reduce the risk of developing late-stage disease (AVRT). Its test, Aristotle, is the first mRNA multi-cancer panel for simultaneously screening for multiple cancers from a single sample of blood with high sensitivity and specificity for each cancer. Aristotle uses mRNA technology to identify the molecular signatures of multiple cancer types and is built on the Company's patented technology platform, the Sentinel Principle. The Care Oncology Clinic offers a supervised treatment regimen (the COC Protocol) for people diagnosed with cancer of any type or stage. Its ColonSentry is a proprietary blood test for screening for Colorectal Cancer.


TSX:SZLS - Post by User

Comment by ScienceFirston Mar 31, 2021 10:46am
187 Views
Post# 32913672

RE:RE:RE:RE:Illumina under fire

RE:RE:RE:RE:Illumina under fireGrail being sued, and the case being heard only August 24, 2021, a judgment will come weeks/months later for them.  So they cannot move until then.

On our side, it's been confirmed by SZLS that our technology doesn't require the key resource that MCED liquid biopsy based technologies are dependent on and that is controled by Illumina.

It smells like a clear sky to us.  

We'll see hear at Aristotle's launch.

_________________

ScienceFirst - (3/31/2021 10:17:31 AM)
RE:RE:RE:Illumina under fire
Confirmed by SZLS;  Aristotle would NOT be dependent, for its Aristotle test, of GRAIL/Illumina's control of a key resource for MCED-based liquid biopsy tests.  Our technology works differently.

_____________________

ScienceFirst
 - (3/31/2021 8:06:30 AM)
RE:RE:Illumina under fire
It will be interesting to see if our technology is dependent on these MCED consumables.  That's THE question to ask.


The complaint alleges the proposed acquisition will diminish innovation in the U.S. market for MCED tests. MCED tests could be used to detect up to 50 types of cancer, most of which are not screened for at all today, saving millions of lives around the world. Grail is one of several competitors racing to develop these liquid biopsy tests, which analyze a sample of a patient’s blood or other fluid through DNA sequencing.

 “The vast majority of cancers, which account for about 80 percent of cancer deaths, are only detected after patients exhibit symptoms. That is often too late to treat effectively,” said FTC Acting Chairwoman Rebecca Kelly Slaughter. “The MCED test is a game changer for cancer patients and their loved ones. If this acquisition is consummated, it would likely reduce innovation in this critical area of healthcare, diminish the quality of MCED tests, and make them more expensive.”

As the only viable supplier of a critical input, Illumina can raise prices charged to Grail competitors for NGS instruments and consumables; impede Grail competitors’ research and development efforts; or refuse or delay executing license agreements that all MCED test developers need to distribute their tests to third-party laboratories. For the specific application at issue in this matter—MCED tests—developers have no choice but to use Illumina NGS instruments and consumables. In December 2019, the FTC challenged Illumina’s proposed acquisition of Pacific Biosciences of California.

The complaint alleges that even if a viable substitute to Illumina’s NGS platform entered the market, it would take years for MCED test developers to switch to a platform other than Illumina’s because they would have to reconfigure their tests to work with the new NGS platform, and in some situations, conduct new clinical trials.

The Commission vote to issue the administrative complaint and to authorize staff to seek a temporary restraining order and preliminary injunction was 4-0. The FTC will file a complaint in the U.S. District Court for the District of Columbia seeking a Temporary Restraining Order and Preliminary Injunction to stop the deal pending an administrative trial. The trial is scheduled to begin on Aug. 24, 2021.

 

The Federal Trade Commission works to promote competition, and protect and educate consumers. 


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