TSXV:CLAS.H - Post by User
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Kobedog1on Apr 01, 2021 10:23am
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Post# 32922299
Read this and also read AngelaL's credentials
Read this and also read AngelaL's credentials This is a repost by AngelaL today that deserves to be shared:
This is tremendous news coming out today. It is well known that NO gas (as in development by Sanotize) is indeed mutagenic in the Ames assay, as described in Mutation Research Letters, Volume 281, 1992, pages 193-202 (entitled "Mutagenicity of nitric oxide and its inhibition by antioxidants"). In contrast, R-107 is now known as of today not to be mutagenic in the Ames Assay. And the reason for this difference is clear: R-107 is a molecule that has an anti-oxidant function built into it (i.e. its nitroxide moiety). R-107 is thus a "dual-function" molecule. So what we may conclude from this is that: 1) there is no way that Sanotize will try to enter the pharmaceutical market (that is why they are going after the consumer market, which doesn't pay well), and 2) R-107 is uniquely poised to be the first nitric oxide donor that is NOT mutagenic. This is home run news. Thank you Bob for this amazing news today.