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ProMIS Neurosciences Inc PMN

ProMIS Neurosciences Inc. is a clinical-stage biotechnology company. It is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). Its proprietary target discovery engine applies a thermodynamic, computational discovery platform-ProMIS and Collective Coordinates-to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product candidates are PMN310, PMN267, and PMN442. The PMN310 is a monoclonal antibody designed to treat AD by selectively targeting toxic, misfolded oligomers of amyloid-beta. PMN267 product candidate targeting ALS. PMN442 is a drug candidate being developed for MSA designed to selectively target and protect against pathogenic a-syn species.


NDAQ:PMN - Post by User

Comment by Speyeder999on Apr 09, 2021 10:42am
187 Views
Post# 32966252

RE:Unique Science

RE:Unique Science

TB does revisit an important topic that has us all holding our breaths of some sorts, but I believe the real questions to ask here are do the tests that Promis sumbitted for approval achieve 99,9% sensitivity and 99,5 specificity% and more importantly do the detected antibodies have neutralizing activity?

I'm amusing that there must already be people in ''the know'' as to the effectiveness of their test and by they, I'm talking about the new investors. My guess is that this SARS CoV-2 test that Promis's has pending for approval tipped the scales for them to embark on the rest of Promis's Unique Science.


The current version of the ProMIS-BCNI antibody test achieves 99.90% sensitivity and 99.50% specificity for SARS CoV-2, the novel coronavirus causing COVID-19 and can be used to detect immune exposure to the virus. But the key step in development of a ‘best in class’ test is to create an assay that not only detects the presence of antibodies specific for the SARS CoV-2 virus but importantly, also allows to determine whether or not the detected antibodies have neutralizing activity, 

 

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