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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Post by askretkaon Apr 19, 2021 9:02pm
226 Views
Post# 33026808

Interesting Bit on CAR-T vs Chemo Costs

Interesting Bit on CAR-T vs Chemo Costs
Found it interesting because Chemo cost is 200k that surprised me. Also CAR-T at 30% not cost effective. But at 40% is. Gee we have something that might help with that. Cheers!--------------------------------------- Dr. Lin:I agree that we should reward therapies that make the biggest difference for our patients. CAR T-cell therapy has resulted in substantial gains for patients in a way that other cancer therapies have not. To your point, one of the flaws in the American health care system is that we pay more than $200,000 per year for non-curative oral chemotherapies but struggle to pay for CAR T cells. Nevertheless, how should we define what price is reasonable for a curative therapy? We have to weigh the outcomes and costs of a therapy simultaneously, and this is the goal of cost-effectiveness analyses. Our analysis showed that CAR T-cell therapies are priced somewhere between intermediate and low value; its ultimate cost-effectiveness depends heavily on cure rate. If 40% of patients are cured with CAR T-cell therapy, it will probably be cost-effective (at a willingness to pay threshold of $150,000 per quality adjusted life year). However, if the cure rate is closer to 30%, it is unlikely to be cost-effective at current prices. Until we have long-term data, I think the jury is still out on whether CAR T-cell therapy is cost-effective.
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