More proof on extended duration of PMX-DHP !
https://read.qxmd.com/read/33910191/impact-of-extended-duration-of-polymyxin-b-immobilized-fiber-column-direct-hemoperfusion-on-hemodynamics-vasoactive-substance-requirement-and-pulmonary-oxygenation-in-patients-with-sepsis-an-observational-study
"DISCUSSION/CONCLUSIONS: Longer duration of PMX-DHP was associated with the improved MAP and decreased volume of vasoactive-inotropic agents compared with the conventional duration. Eight and longer hours duration of PMX-DHP was associated with the improvement in the pulmonary oxygenation. Further studies are needed to confirm the efficacy of longer duration of PMX-DHP in patients with septic shock."
Three points:
Who knew that by removing more endotoxins (perhaps until the infection sourse has been adequantely controlled) would improve outcomes?
Wonder how the FDA will deal with this complelling new real world evidence as they finalize their reiew of Tigris results?
Would using more filters or higher capacity filters increase the long term revenues of Spectral assuming FDA approva? Hmmmm?!
MM