RE:RE:RE:RE:any thoughtsFrom what I understand the top-up is part of the clinical trial protocol. Until they get their dosing right, they will continue doing top-ups. Picture it from a patients POV. WOuld you want to go on the immunosuppressants and all this trouble if you didn't know if the procedure would work or not? Because of this (IMO), they are ending the trial with portal vien so the trial candidates at least get that benefit at the end. Even 40 percent reduction of insulin is huge. Maybe when they dial in the correct dose, it could work even better. Remember these are patients with 0 insulin production. If they get the immuno tech down and are able to insert pouches into patients who are borderline or mild diabetics, it could potentially cure them.