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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy. Its portfolio includes Phase I clinical trial of sudocetaxel zendusortide (TH1902), a novel peptide-drug conjugate (PDC), in patients with advanced ovarian cancer.


TSX:TH - Post by User

Comment by qwerty22on Jun 03, 2021 1:34pm
104 Views
Post# 33319905

RE:RE:RE:RE:RE:RE:RE:RE:Great

RE:RE:RE:RE:RE:RE:RE:RE:Great

I'm with you. It seems to me highly likely the program will change quite radically after the Ph1 data so that details on the market might quickly become irrelevant.


I know you've talked about an LSA report before, did Paul say there would be a public report published? I missed that.


SPCEO1 wrote: I am quite curious to see what LSA's report looks like. It may be too early for them to start talking about the market opportunity for TH-1902 in anything other than broad strokes. But maybe not. Hopefully, we will soon see.  Perhaps the LSA report will come out prior to 6/21. 
 

scarlet1967 wrote: My questions wasn't really related to the science or the trial itself as I am sure they will address both, as  a big fan of marketing  the programs by giving some insights re the financial opportunities of the protocol although this is more of the KOL's opinion about the drug I want someone on the webinar for instance if CEO or CMO are present to shed some light on the financial opportunities. I also hope the report addresses those opportunities after all it's produced to be presented to investors.


SPCEO1 wrote: Plenty of time to formulate questions, so no need to rush on that Scarlett. Also, it is concievable that the date was picked because there will be nformation announced on new cancer reserach THTX has completed before then. If so, that might change the questions you want to submit so putting questions in too soon may be unproductive. 

THTX is trying to rebrand the stock. It is a big job and they have a good group in LSA to ehlp them do that. My guess is that there will be some notable news release prior to the actual 6/21 event that will help bring people, other than loyal long term sharehodlers like ourselves, to it. Hopefully, that is the way it plays out. 

We also still have the NASH phase II protocol news. I guess we are at the mercy fo the EMA in terms of when we get that news but it likely cannot be too far off now.

qwerty22 wrote:

18 days to go

 

scarlet1967 wrote: I did submit some questions, I find it odd that they didn't issue a PR or posting the news on their social media platforms!
 

 

Wino115 wrote: Keep it coming THTX/LSA.  Information to aid in evaluating the company's pipeline is crucial.  There's a button to send in questinos prior to the event.  We should think about the most important issues for the whole SORT1+ and the Phase 1 trial and submit them.  Better to get the best questions in so they are answered and not innundate them with too many.  

Science minds, start thinking!


SPCEO1 wrote: Excellent news! TH continues to lead with cancer versus NASH which likely indicates things are following an encouraging path so far in the cancer phase I trial.
scarlet1967 wrote:

In case you did not receive this already, please see below for information on an upcoming investor event highlighting our SORT1+ Technology, featuring key opinion leader Dr. Richard Beliveau, taking place on Monday, June 21, 2021 at 11:00am ET

The webinar will feature a presentation by Key Opinion Leader (KOL) Richard Bliveau, Ph.D. (Universit du Qubec Montral) who will discuss the science of receptor-mediated cancer therapy and the discovery of sortilin as a novel target in cancer treatment. Dr. Bliveau will be available to answer questions following the formal presentations.

 

Theratechnologies' management team will also give an update on their oncology pipeline including TH1902, the Company's lead investigational peptide-drug conjugate (PDC) stemming from its SORT1+ Technology™ in oncology. SORT1+ Technology is a new class of cancer treatment targeting all sortilin-expressing cancers by linking approved anticancer drugs to a proprietary peptide that specifically binds to the sortilin receptor. The PDC is internalized by the sortilin receptor and the therapeutic agent is released directly inside the cancer cell. TH1902 was granted fast track designation by the U.S. Food and Drug Administration (FDA) as a single agent for the treatment of all advanced solid tumors expressing sortilin that are refractory to standard therapy and is currently being evaluated in a Phase 1 clinical trial.

 

 


 

 

 

 

 

 




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