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Antibe Therapeutics Inc(Pre-Merger) ATBPF

Antibe Therapeutics Inc. is a clinical-stage biotechnology company. The Company is leveraging its hydrogen sulfide (H2S) platform to develop therapies to target inflammation arising from a range of medical conditions. The Company’s pipeline includes assets that seek to overcome the gastrointestinal ulcers and bleeding associated with nonsteroidal anti-inflammatory drugs (NSAIDs). Its lead drug, otenaproxesul, is in clinical development as an alternative to opioids and NSAIDs for acute pain. Its second pipeline drug, ATB-352, is being developed for a specialized pain indication. The Company also focuses on inflammatory bowel disease (IBD). Otenaproxesul combines a moiety that releases hydrogen sulfide with naproxen, a non-steroidal, anti-inflammatory drug. ATB-352 is an H2S-releasing derivative of ketoprofen, a potent NSAID commonly prescribed for acute pain. Its IBD candidates are being designed to maintain the efficacy, safety, and pharmacokinetic properties of ATB-429.


GREY:ATBPF - Post by User

Comment by MrMugsyon Jun 04, 2021 2:31pm
117 Views
Post# 33331106

RE:nosh

RE:nosh
Nick80 wrote: Hi what are you guys think about:
https://www.avicennatherapeutics.com/technology

Would they be serious competition for ate 346, 352 or 340?

From my understanding their platform might outperform ATE's 340 drug if successful, however what about 346 and others? 

Their nosh platform is in pre-clinical only meaning ate is very well advanced and derisked compared to them... 


At first glance Nick ... I personally won't be losing sleep over it.

Not only is Wallace on their advisory board, he's also discussing the potential of NOSH-NSAIDs openly in his papers.  For him to be on their board, he sees no conflict and he obviously hasn't raised a conflict of interest.

Also, this company seems to be focusing on cancer alone (as per their website information).
-----

Keep in mind too that ATE is in a drug discovery period and with their academic partner and their skillset, we could be well past NOSH designs.  If ATE is looking at nano-partilces, bottlebrush, etc... in some tunable form ... we may be in great shape.

There's lots the company needs to share - I'm sure.

I am looking into Avicenna ... just haven't learned much else yet.  Anyone ?



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