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ProMIS Neurosciences Inc PMN

ProMIS Neurosciences Inc. is a clinical-stage biotechnology company. It is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). Its proprietary target discovery engine applies a thermodynamic, computational discovery platform-ProMIS and Collective Coordinates-to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product candidates are PMN310, PMN267, and PMN442. The PMN310 is a monoclonal antibody designed to treat AD by selectively targeting toxic, misfolded oligomers of amyloid-beta. PMN267 product candidate targeting ALS. PMN442 is a drug candidate being developed for MSA designed to selectively target and protect against pathogenic a-syn species.


NDAQ:PMN - Post by User

Comment by Gbathaton Jun 08, 2021 1:42pm
145 Views
Post# 33348610

RE:RE:Share price should be $5.50

RE:RE:Share price should be $5.50 Today, perhaps.  After a phase 1 deal announcement, not at all.

The global AD therapy market is $25B.  Let's assume PMN is only going to capture 20%, so $5B. At 20% profit margin, they earn $1B.

At a p/e of 20, their market cap is then $20B.

Their current market cap is $70M, heck, let's round up to $100M to account for pending partnership dilution effect.

$20B divided by $100M is a 200-fold increase in share price.

our current share price of 20 cents times 200 gives $40/share.

Vandermosten's analysis used a probability of success of 7% based on analysis of the technology and its maturity.

If you multiply 7% by $40, you come in around $2.80 USD... Not too far from his original estimate.

As they proceed through phase 1 and 2 and 3, that probability of success goes up.

Basically, the current share price is telling us the current probability of success is less than 1%, which in my opinion is extremely conservative, especially now that aducanumab is approved.

Do your own ed and check my math.  These are just my personal opinions and I am not an investment advisor.


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