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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy. Its portfolio includes Phase I clinical trial of sudocetaxel zendusortide (TH1902), a novel peptide-drug conjugate (PDC), in patients with advanced ovarian cancer.


TSX:TH - Post by User

Comment by jfm1330on Jun 09, 2021 12:35pm
123 Views
Post# 33355515

RE:RE:RE:RE:RE:RE:RE:RE:Sad news

RE:RE:RE:RE:RE:RE:RE:RE:Sad newsThis is the reverse side of the publicity made on the first dosing on this patient. It also put forward the question as to why they are not testing patients for sortilin overexpression on tumors before selecting them? In this case, it was even worse, they took a type of cancer that was never in their list of cancers with possible sortilin overexpression. Also, the doses that he was given are the lowest possible ones, so probably unefficacious even on a patient with the proper cancer. That being said, maybe the patient decided to make an altruistic action knowing it would not change much for him, but it would be his last contribution in helping other. A way to give a purpose to his last weeks on earth, So I thank him for that.

Now, Thera needs to get serious and start testing for sortilin overexpression on the tumors of the patients they will select. Levesque said in his last chat that they will do it later on in the phase I. In my view, they need to start doing it right now! Making sure to keep the whole thing private would also be a good idea.


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