Big 2 weeks ahead COLD CHAIN • The Company has received cold chain ELISA data from the Food and Drug Administration (“FDA”) Polio Research Lab and is currently coordinating an analysis review session with the FDA and establishing the related communications.
The Company has filed the Porous Aluminum Nano-Structured Adjuvant patent to support its advanced vaccine dose sparing work. • The Company has executed a study, comparing existing Alhydrogel adjuvant to the Company’s invented stable nano-particulate adjuvant by both intramuscular injection and intradermal injection immunization, evaluating the antibody responses following vaccination with fractional doses of IPV comparing delivery types with IPV alone or adjuvanted. • The results from the study being conducted at Tulane University School of Medicine in New Orleans, Louisiana, United States is anticipated by the end of May or early June.
HUSBANDRY ANIMALS • The Company has commenced husbandry animal trials validate the superiority of its injectable solubilized Ivermectin technology, Ivectosol™ 1%, versus current commercially available forms to treat a broad category of animal parasites. • The trials have commenced in Canada to study poultry, swine and cattle, and in Bangladesh to study poultry, goat and cattle. Initial feedback is the trial dosing was easily accomplished in the animals with the needleless applicator with no adverse reactions. • The preliminary study results for Canada are anticipated late June, 2021. The preliminary study results for Bangladesh are anticipated early June, 2021. ONCOLOGY • The Company has filed the cancer patent for direct intratumoral injection, intravenously, infusions or instillations as adjuvants for broad chemotherapeutic to immunotherapeutic cancer regimens. • Separate pre-clinical trials for triple-negative breast cancer, metastatic melanoma and Lewis Lung Carcinoma are being conducted and the Company anticipates preliminary results for the studies later in June. “Receiving early feedback confirming the ability to safely inject Ivectosol™ 1% across poultry, swine, goat and cattle our initial animal trials is very encouraging and validates the pathway we are pursuing in human applications such as oncology and COVID-19,” stated Dennis Hancock, President and CEO of Mountain Valley MD. “I am very proud of the team and our research partners for this incredible progress across multiple lanes of innovation. We couldn’t be more honoured to drive forward this important work.”