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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy. Its portfolio includes Phase I clinical trial of sudocetaxel zendusortide (TH1902), a novel peptide-drug conjugate (PDC), in patients with advanced ovarian cancer.


TSX:TH - Post by User

Comment by qwerty22on Jun 23, 2021 8:14am
124 Views
Post# 33433170

RE:Question

RE:Question

Sortilin is best known as a brain protein, it's expressed on the surface of neurons. I would think one of the first things you look at is does it cross the BBB. If Katana/thtx haven't ticked this off the to do list early in the process then we are invested in fools. Could they have not done this? Are they all fools?

SABBOBCAT wrote: Wasn't Katana working on peptides to cross the blood bran barrier before selling the platform to TH? Is there any risk that the PDC would cross the BBB and have into tended side effects?

 

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