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Antibe Therapeutics Inc(Pre-Merger) ATBPF

Antibe Therapeutics Inc. is a clinical-stage biotechnology company. The Company is leveraging its hydrogen sulfide (H2S) platform to develop therapies to target inflammation arising from a range of medical conditions. The Company’s pipeline includes assets that seek to overcome the gastrointestinal ulcers and bleeding associated with nonsteroidal anti-inflammatory drugs (NSAIDs). Its lead drug, otenaproxesul, is in clinical development as an alternative to opioids and NSAIDs for acute pain. Its second pipeline drug, ATB-352, is being developed for a specialized pain indication. The Company also focuses on inflammatory bowel disease (IBD). Otenaproxesul combines a moiety that releases hydrogen sulfide with naproxen, a non-steroidal, anti-inflammatory drug. ATB-352 is an H2S-releasing derivative of ketoprofen, a potent NSAID commonly prescribed for acute pain. Its IBD candidates are being designed to maintain the efficacy, safety, and pharmacokinetic properties of ATB-429.


GREY:ATBPF - Post by User

Comment by MrMugsyon Jun 24, 2021 10:20am
130 Views
Post# 33441000

RE:RE:RE:RE:RE:Conference Call Tomorrow ...

RE:RE:RE:RE:RE:Conference Call Tomorrow ...
CalgaryATE wrote:
MrMugsy wrote:
GameChangerBet wrote: No new material from what I heard.
Although reassuring of all the material positives in the near-intermmediate term. 

themagicbox wrote: were you able to catch it any details? It just ended.

MrMugsy wrote: Raymond James tomorrow at 8:40 AM.

Based on the Bear Creek call today - sounds like a few things might be made a little clearer tomorrow (from what others are saying).

Someone remind Yukon not to take my advice ... he's too good to take that call anyway.

: )

 

 


Finished off the discussion with a reminder that OTENA peak sales of $4B is in reference to OA in 4 markets.  Looking at all indications ... OTENA is probably looking at $10B for peak.  If I understood that final comment. 

Only had time for two questions


After listening to it at my leisure tonight, the first question & answer was in regards to how were they planning on handling the placebo effect.  A little bit more detail on the 2nd question was:

Q (29:00):  Total addressable market is far more significant beyond OA, plans for label expansion beyond OA?
 
A:  (29:30):  graph on investor deck ($4 billion US sales at peak), only for 7 markets (5 in Europe, US & Japan, representing 65% of the world) and only for OA (about 50% of the overall chronic pain indication).  Going to go after all of it.  OA is solid and robust, great way to go after initial marketing approval with FDA and other agencies.  As they're reviewing the file, we will rapidly do the other studies (they're smaller), go after rheumatoid arthritis and ankylosing spondylitis and other chronic pain indications (same size as the OA market), will constantly be doing that.  At 21% adoption could be seeing peak sales of close to 10 billion dollars per year.

https://kvgo.com/rj-health/antibe-therapeutics-inc-june-2021


And that's why we needed cash in the bank ... to buy time ... to have the ability to go into Phase 3 without Big Pharma giving us the gears to accept a less-than-optimal deal.

I'd like to think we're driving this bus.  Slowly but surely, we'll get to our destination.  IMO.
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