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ProMIS Neurosciences Inc PMN

ProMIS Neurosciences Inc. is a clinical-stage biotechnology company. It is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). Its proprietary target discovery engine applies a thermodynamic, computational discovery platform-ProMIS and Collective Coordinates-to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product candidates are PMN310, PMN267, and PMN442. The PMN310 is a monoclonal antibody designed to treat AD by selectively targeting toxic, misfolded oligomers of amyloid-beta. PMN267 product candidate targeting ALS. PMN442 is a drug candidate being developed for MSA designed to selectively target and protect against pathogenic a-syn species.


NDAQ:PMN - Post by User

Comment by retiredcopon Jun 26, 2021 7:50am
203 Views
Post# 33455599

RE:RE:U.S. lawmakers to investigate approval, pricing of Alzheimer

RE:RE:U.S. lawmakers to investigate approval, pricing of AlzheimerSo we move into a potential opportunity where PMN310 could prove that they have a drug that works better then Aduhelm and has addressed the concerning side effects Aduhelm has...but even more desirable with this recent controversy,  a drug that will cost much less then the Aduhelm .  I go back to a few years ago when PMN first revealed their completed PMN310.... for some reason I remember hearing this number a few times from various people talking around the camp fire having a beer.... " $4 a dose to manufacture" . Look at it this way ..  Biogen and others before have been the ones that have invested 100"s millions of dollars in  R&D in the development and clinicals for their AD drugs. PMN has taken the approach of waiting and watching what happens with each expensive process and then tweeking PMN310 to deal with shortcomings identified by the other companies. These other companies have done all our expensive work . Those expenses have to be recovered , so how do you do it... charge some pretty high prices on the end product. I could see PMN coming out with some really amazing prices compared to these other large companies .. dont get me wrong .. the prices could be significantly lower then our competitors but still rediculously profitable , when you look at money spent on R&D and money returning. Again you turn the public opinion with something everybody is fcusing on  1) product that works better with little or no known sdieeffects     2) a price that is considered more then exceptable by these concerned people. 
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