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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy. Its portfolio includes Phase I clinical trial of sudocetaxel zendusortide (TH1902), a novel peptide-drug conjugate (PDC), in patients with advanced ovarian cancer.


TSX:TH - Post by User

Comment by jfm1330on Jul 18, 2021 4:00pm
127 Views
Post# 33567141

RE:RE:Dose escalation

RE:RE:Dose escalationThe only explaination would be that docetaxel is not efficacious against certain type of cancers, but it is hard to imagine it would not work against every cancers. That's why the scientific logic leads to think that if the MTD is high, efficacy should be there.


stockman75 wrote:
Jfm thanks for this great information/analysis. From a scientific perspective how would you explain a scenario where they have such large MTD dosage and NOT have very good efficacy (for sortllin expressing cancers)? Thanks


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