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ProMIS Neurosciences Inc PMN

ProMIS Neurosciences Inc. is a clinical-stage biotechnology company. It is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). Its proprietary target discovery engine applies a thermodynamic, computational discovery platform-ProMIS and Collective Coordinates-to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product candidates are PMN310, PMN267, and PMN442. The PMN310 is a monoclonal antibody designed to treat AD by selectively targeting toxic, misfolded oligomers of amyloid-beta. PMN267 product candidate targeting ALS. PMN442 is a drug candidate being developed for MSA designed to selectively target and protect against pathogenic a-syn species.


NDAQ:PMN - Post by User

Comment by retiredcopon Jul 22, 2021 7:59pm
96 Views
Post# 33594369

RE:RE:Upcoming Alzheimer's conference

RE:RE:Upcoming Alzheimer's conference

TORONTO and CAMBRIDGE, Mass., July 22, 2021 (GLOBE NEWSWIRE) -- ProMIS Neurosciences, Inc. (TSX: PMN) (OTCQB: ARFXF), a biotechnology company focused on the discovery and development of antibody therapeutics targeting toxic oligomers implicated in the development of neurodegenerative diseases, will give two presentations at the annual Alzheimer’s Association International Conference (AAIC®) to be held July 26-30, 2021 in Denver, USA and online.

ProMIS Chief Scientific Officer, Dr. Neil Cashman will give an oral presentation entitled: “Selective targeting of intracellular misfolded, pathogenic TDP-43 with rationally designed intrabodies.” Dr. Cashman will deliver this presentation and chair the Virtual Oral Session #55269 to be held on Thursday, July 29, from 1:00 PM – 2:15 PM MT.

Dr. Johanne Kaplan, ProMIS Chief Development Officer, will present the poster entitled: “Conformational epitopes exposed on misfolded toxic forms of amyloid-beta, tau and alpha-synuclein directly contribute to their seeding activity.” The poster discusses conformational epitopes on misfolded proteins that represent unique targets for therapeutic antibodies. Dr. Kaplan will deliver her poster presentation in person in Denver and online. Please consult the AAIC® website (https://alz.org/aaic/overview.asp) for venue, date and time of the presentation.

Both presentations will be available on the ProMIS website (www.promisneurosciences.com) after the AAIC® closes on July 30.

AAIC® is the largest, most influential international meeting focused on advancing dementia science. The annual conference convenes the world’s leading basic science and clinical researchers, next-generation investigators, clinicians and the care community to share research discoveries supporting new methods of prevention, treatment and diagnosis of Alzheimer’s disease.

 
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