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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy. Its portfolio includes Phase I clinical trial of sudocetaxel zendusortide (TH1902), a novel peptide-drug conjugate (PDC), in patients with advanced ovarian cancer.


TSX:TH - Post by User

Comment by jfm1330on Jul 26, 2021 12:21pm
102 Views
Post# 33604613

RE:Theranostics

RE:TheranosticsThis is exactly what I am talking about relentlessly here, but for prostate cancer. Personnally, I was talking about neuroendocrine cancers, which was the cancer for which the first PDCs developped with radioisotopes. In this case it's a more recent development in prostate cancer. It uses a tripeptide linked to a non peptidic part. This peptide based molecule has affinity for the PSMA receptor overexpressed in prostate cancer. The rest is the same. They use the DOTA linker to chelate the isotopes. They now have the imaging version with Gallium 68, the therapeutic version with Lutetium 177, and they already do trials with Actinium 225. Wake up Marsolais and Thera!!!!


https://www.researchgate.net/figure/Chemical-structures-of-DOTAGA-FFKSub-KuE-a-first-generation-tracer-upper-and-PSMA_fig3_278788852


Lee430 wrote: Molecular-targeted liquid radiation, is this simular to what jfm1330 has been refering to that Thera could use with the peptide or a completly different new therapy? 

https://www.dailybulletin.com/2021/07/24/new-hope-in-the-fight-against-prostate-cancer-we-can-win-this-war/



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