GREY:ATBPF - Post by User
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WalkOverTheStrton Aug 03, 2021 10:34pm
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Post# 33646758
Some research on what can cause these issues...
Some research on what can cause these issues...Worth reading into elevated transaminase levels
Study that shows how acetaminophen can cause liver transaminase elevations exceeding normal ranges (this study was 3x more)
Results None of the 39 participants assigned to placebo had a maximum ALT of more than 3 times the upper limit of normal. In contrast, the incidence of maximum ALT of more than 3 times the upper limits of normal was 31% to 44% in the 4 treatment groups receiving acetaminophen, including those participants treated with acetaminophen alone.
https://jamanetwork.com/journals/jama/fullarticle/211014
Most common reasons for liver transaminase elevations:
"The most common causes of elevated transaminase levels are nonalcoholic fatty liver disease and alcoholic liver disease. Uncommon causes include drug-induced liver injury, hepatitis B and C, and hereditary hemochromatosis. Rare causes include alpha1-antitrypsin deficiency, autoimmune hepatitis, and Wilson disease.
Mild, asymptomatic elevations (less than five times the upper limit of normal) of alanine transaminase and aspartate transaminase levels are common in primary care. It is estimated that approximately 10% of the U.S. population has elevated transaminase levels. An approach based on the prevalence of diseases that cause asymptomatic transaminase elevations can help clinicians efficiently identify common and serious liver disease. The most common causes of elevated transaminase levels are nonalcoholic fatty liver disease and alcoholic liver disease. Uncommon causes include drug-induced liver injury, hepatitis B and C, and hereditary hemochromatosis. Rare causes include alpha1-antitrypsin deficiency, autoimmune hepatitis, and Wilson disease. Extrahepatic sources, such as thyroid disorders, celiac sprue, hemolysis, and muscle disorders, are also associated with mildly elevated transaminase levels.
https://www.aafp.org/afp/2017/1201/p709.html
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719197/