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ProMIS Neurosciences Inc PMN

ProMIS Neurosciences Inc. is a clinical-stage biotechnology company. It is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). Its proprietary target discovery engine applies a thermodynamic, computational discovery platform-ProMIS and Collective Coordinates-to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product candidates are PMN310, PMN267, and PMN442. The PMN310 is a monoclonal antibody designed to treat AD by selectively targeting toxic, misfolded oligomers of amyloid-beta. PMN267 product candidate targeting ALS. PMN442 is a drug candidate being developed for MSA designed to selectively target and protect against pathogenic a-syn species.


NDAQ:PMN - Post by User

Comment by Thenorth1990on Aug 10, 2021 6:29pm
134 Views
Post# 33682539

RE:How much is needed to start Phase I?

RE:How much is needed to start Phase I?The following table provides an overview of the estimated expenditures required for the Company to advance its PMN310 monoclonal antibody into a clinical trial and, subject to approval of an IND application, complete Phase 1. The Company cautions readers that such information is forward-looking in nature and is qualified in its entirety by the risk factors and other disclosure set-out under “Risk Factors” and any other factors set forth in the Company’s public disclosure. Further, as preparing, submitting, and advancing applications for regulatory approval, developing products and processes and clinical trials are complex, costly, and time-consuming processes, the Company has only provided an estimated range of the future costs. Amyloid-β Oligomer Use of Existing Cash Resources (Next 12 Months) Preclinical Development (2) Clinical Trial Phase 1 Total Additional Capital (3) PMN310 $1,156,917 (1) $9 Million to $14 Million $14 Million to $24 Million $23 Mill

page 11, short form prospectus 
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