GREY:ATBPF - Post by User
Comment by
MrMugsyon Aug 11, 2021 1:59pm
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Post# 33685686
RE:Webinar for tmrrw
RE:Webinar for tmrrwthemagicbox wrote: Given that the old dumpster is back to his antics, lets bring some graded expectations to this:
-this webinar was already planned in advance and theyre unlikely to have the answer to the unexpected ALT elevation.
-the ALT elevation are in only in 3 people out fo the 35 people who are in the cohort i.e. 8%. And was not a serious adverse event i.e. unlike the hep guy from ph1, no one went to the hospital.
-given that its 8%, thats in line with general population having elevated ALTs as their base which is usually due to behavioral/lifestyle (we actually dont know how they screened the patients) or is "idiopathic".
-Lets assume its the drug and its due to the half life. Even if it is the drug/half life, in the past they've shown the half life to be related to efficacy so it may just be a case of requiring further dose titration. Which was already going to be the focus of both this AME and the first ph3 trial
The reality is they paused because of they hit a prespecified precautionary trigger and some people were still on dose for 1 more week, so by design they have to pause before letting those other people continue dose.
Be careful with the FUD from duster, yukonjizza (my favorite clowns on this board) and the other dervative NPCs haha. They just want the cheap shares. Dumspter is porbably kicking himself in the a$$ for not accumulating enough below the $1 mark. Turd.
Amen Brother ... Someone who gets it.
Sure this is all strange but it's also very foreign terrain.
Though I am here for the drugs - don't get me wrong on that.
I also know we have the cash to carry us through the hurdles.
We have a capable team.
Most importantly, we have options - and - it's the full package that gets us where we need to go.
The old days of panic are gone because we have access to the resources we need.
Thankfully.