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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Healthcare Biotechnology
Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy. Its portfolio includes Phase I clinical trial of sudocetaxel zendusortide (TH1902), a novel peptide-drug conjugate (PDC), in patients with advanced ovarian cancer.


TSX:TH - Post by User

Theratechnologies Inc > Whats this?
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Comment by jfm1330on Aug 13, 2021 3:31pm
101 Views
Post# 33702086

RE:RE:RE:RE:RE:RE:RE:RE:RE:Whats this?

RE:RE:RE:RE:RE:RE:RE:RE:RE:Whats this?Reading the article I noticed that the xenograft tumors on which TH1902 was tested had a volume of around 100 mm3, so 0.1 ml. This is minuscule. There is no way it can validate tumor penetration on humans. It is so small in comparison with most human tumors that will be treated. Also, they are created from a single cell line, so these tumors are genetically homogenous. That explains in good part why the jump from such minuscule xenograft tumors to real tumors on real patients is such a huge jump. 
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