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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Post by Noteableon Aug 19, 2021 11:39am
160 Views
Post# 33730469

Why companies do not take random calls from "investors'

Why companies do not take random calls from "investors'The following has been reported in Fiercebiotech on why late stage biotech companies don't take unsolicited calls from "investors" further to the rising level of FDA and SEC scrutiny on all companies, as exemplified by the linked report .... “At the macro level, there is an unprecedented level of scrutiny at the FDA. Maybe the most scrutiny we’ve seen since the early 1960s,”

The company Sesen (formerly Eleven Biotechnology) is in the development of antibody drug conjugates (ADC). I had commented on the issues of ADCs on the Yahoo message board before my posts kept being deleted. I also pointed out that ONCY's oncolytic virus pelareorep was able to enable CAR-T and bispecific therapies in solid tumors, making those treatments effective in various forms of solid tumors, by overcoming the immunosuppressive tumor microenvironment (TME), thus turning a cold tumor "hot", and by facilitating T-cell infiltration into the cancer cell, resulting in effective killing of the cancer cell, as several mechanisms of pelareorep's action 


https://www.fiercebiotech.com/biotech/sesen-bio-shares-crater-after-repot-trial-misconduct-for-bladder-cancer-drug

Vicinium, a next-generation antibody-drug conjugate, is being developed as an alternative to losing the bladder

https://www.fiercebiotech.com/struggling-eleven-bio-cashes-out-2nd-drug-270m-roche-deal
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