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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy. Its portfolio includes Phase I clinical trial of sudocetaxel zendusortide (TH1902), a novel peptide-drug conjugate (PDC), in patients with advanced ovarian cancer.


TSX:TH - Post by User

Comment by SPCEO1on Sep 30, 2021 10:52pm
209 Views
Post# 33950841

RE:RE:RE:RE:RE:Examples of efficacy from dose escalation studies

RE:RE:RE:RE:RE:Examples of efficacy from dose escalation studiesBelow is a more comprehensive quote from my post which I believe better characterizes what I was saying than just the portion you quoted. Do you think that the way Paul has characterized the cancer phase 1a so far can't be described as optimistic? Granted he has given us no actual data on the phase 1a but he has clearly built expectations of a positive result with pretty effusive comments. Here is what I posted earlier: Let's hope they do better this time around, regain their credibility and move onto many bigger and better things. If they have nothing in cancer to "tout" as Paul said yesterday, then Paul's credibility is going to fall another few notches lower since he has been consistently very positive in the way he has generally characterized the cancer phase 1a trial. Hopefully, the specific data coming from the trial, whenever they get around to telling us more, will back up those favorable comments. On the issue of what data they may already have, if there was a response when they were doling out lower doses to the patients, as the pre-clinical work suggested there would be, they would already know that. One issue, however, is did those earlier patients who were treated with lower doses survive long enough to have enough treatments to show an effect. My sense at the cancer KOL was that they had already begun to see some efficacy signals and the talk about wanting to rpove such things up in the right way also indicates they have seen something. Or they are just speking in an optimisitc manner that intentionally is creating a perception of success in the trial when no success has yet been seen? While they have shown a willingness to distort the truth in the past, I am hoping they learned from those mistakes.
palinc2000 wrote: Spceo wrote
Or they are just speking in an optimisitc manner that intentionally is creating a perception of success in the trial when no success has yet been seen? While they have shown a willingness to distort the truth in the past, I am hoping they learned from those mistakes. " 

I must have missed the optimism about clinical results in Oncology.All I heard is optimism on  the potential of the Platform in treating cancer IF clinical results are similar to pre clinical results....




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