Gasser Group's New Approach to PDC Delivery to Cancer CellsThe
Gasser Group at the
Chimie Paris Tech led by Gilles Gasser is very similar to the
MccFarland Research Group at the
University of Texas Arlington led by Sherri McFarland. They are both investigating the use of metal complexes for medicinal purposes.
In this recent article they explore a new cancer specific photodynamic drug delivery system by coupling a
ruthenium based photosensitizer with the
aptamer AS1411.
Aptamers are molecules which bind to specific targets and
AS1411 has been demonstrated to bind to breast and prostate cancer cells leaving normal cell lines unaffected.
Abstract -
A ruthenium-oligonucleotide bioconjugated photosensitizing aptamer for cancer cell specific photodynamic therapy Full paper -
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