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Satellos Bioscience Inc T.MSCL

Alternate Symbol(s):  MSCLF

Satellos Bioscience Inc. is a Canada-based biotechnology company. The Company is engaged in developing new small molecule therapeutic approaches to improve the treatment of muscle diseases and disorders. The Company is focused on the research in muscle stem cell polarity into a proprietary discovery platform, called MyoReGenX, to identify degenerative muscle diseases where deficits in this process affect muscle regeneration and are amenable to therapeutic intervention. With this platform, the Company is building a pipeline of therapeutics to correct muscle stem cell polarity and promote the body’s innate muscle repair and regeneration process. The Company’s lead program is an oral, small molecule drug candidate in development as a potential disease-modifying treatment for Duchenne muscular dystrophy. It has wholly owned subsidiaries in Australia (Satellos Bioscience Australia Pty Ltd), in Canada (Amphotericin B Technologies, Inc.) and in Delaware, USA (Satellos Bioscience US, Inc.).


TSX:MSCL - Post by User

Post by db2067on Nov 25, 2021 10:04pm
221 Views
Post# 34167325

Satellos / U of T connection

Satellos / U of T connectionSome of the work happening here at U of T is for Satellos - testing on human muscle tissue - sort of a big deal - "... to enable human testing of candidate drugs in a ‘personalized’ culture assay, we will incorporate induced pluripotent stem cells, derived from DMD patients, to create DMD MEndR, and then use this assay to evaluate Satellos’ lead therapeutic compounds." UNIVERSITY OF TORONTO ENGINEERING NEWS U of T researchers’ lab-grown muscles used to study Duchenne muscular dystrophy, develop treatments
https://news.engineering.utoronto.ca/u-of-t-researchers-lab-grown-muscles-used-to-study-duchenne-muscular-dystrophy-develop-treatments/

Inside a Petri dish in a lab at the University of Toronto is a muscle — made from scratch using human stem cells — that has Duchenne muscular dystrophy (DMD). ... “The DMD pre-clinical assays being developed by Gilbert and Stewart are a critical facet of the translational pipeline, making it possible to test current and future therapeutics in the context of human cells,” says Dr. Rudnicki [Satellos], senior scientist and director of the regenerative medicine program and Sprott Centre for Stem Cell Research at the Ottawa Hospital Research Institute.
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