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Satellos Bioscience Inc T.MSCL

Alternate Symbol(s):  MSCLF

Healthcare Biotechnology
Satellos Bioscience Inc. is a Canada-based a drug discovery and development company with a focus on muscle regeneration. The Company is focused on developing medicines to treat degenerative muscle conditions. Its MyoReGenX platform is specifically designed to recreate the specialized muscle stem cell niche in vitro. MyoReGenX platform enables to map pathways which modulate muscle repair and regeneration, identify, and confirm drug targets, and test drug candidates for their ability to restore muscle stem cell repair mechanisms that have been impaired by genetic mutations, disease or injury. Its lead program is an oral, small molecule drug candidate in development as a disease-modifying treatment for Duchenne muscular dystrophy. Its iCo portfolio includes Oral Amp B Delivery System, a patented oral transport technology and Bertilimumab a human monoclonal eotaxin antibody with potential to treat a range of allergic and inflammatory conditions mediated by eotaxin-1.


TSX:MSCL - Post by User

Satellos Bioscience Inc
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Post by db2067on Nov 25, 2021 10:04pm
199 Views
Post# 34167325

Satellos / U of T connection

Satellos / U of T connectionSome of the work happening here at U of T is for Satellos - testing on human muscle tissue - sort of a big deal - "... to enable human testing of candidate drugs in a ‘personalized’ culture assay, we will incorporate induced pluripotent stem cells, derived from DMD patients, to create DMD MEndR, and then use this assay to evaluate Satellos’ lead therapeutic compounds." UNIVERSITY OF TORONTO ENGINEERING NEWS U of T researchers’ lab-grown muscles used to study Duchenne muscular dystrophy, develop treatments
https://news.engineering.utoronto.ca/u-of-t-researchers-lab-grown-muscles-used-to-study-duchenne-muscular-dystrophy-develop-treatments/

Inside a Petri dish in a lab at the University of Toronto is a muscle — made from scratch using human stem cells — that has Duchenne muscular dystrophy (DMD). ... “The DMD pre-clinical assays being developed by Gilbert and Stewart are a critical facet of the translational pipeline, making it possible to test current and future therapeutics in the context of human cells,” says Dr. Rudnicki [Satellos], senior scientist and director of the regenerative medicine program and Sprott Centre for Stem Cell Research at the Ottawa Hospital Research Institute.
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