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Theralase Technologies Inc. V.TLT

Alternate Symbol(s):  TLTFF

Healthcare Medical Devices
Theralase Technologies Inc. is a Canada-based clinical-stage pharmaceutical company. The Company is engaged in the research and development of light activated compounds and their associated drug formulations. The Company operates through two divisions: Anti-Cancer Therapy (ACT) and Cool Laser Therapy (CLT). The Anti-Cancer Therapy division develops patented, and patent pending drugs, called Photo Dynamic Compounds (PDCs) and activates them with patent pending laser technology to destroy specifically targeted cancers, bacteria and viruses. The CLT division is responsible for the Company’s medical laser business. The Cool Laser Therapy division designs, develops, manufactures and markets super-pulsed laser technology indicated for the healing of chronic knee pain. The technology has been used off-label for healing numerous nerve, muscle and joint conditions. The Company develops products both internally and using the assistance of specialist external resources.


TSXV:TLT - Post by User

Theralase Technologies Inc.
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Post by enriquesuaveon Dec 03, 2021 12:12pm
513 Views
Post# 34195290

Prevalence of UTUC in NMIBC patients

Prevalence of UTUC in NMIBC patients This bodes very well for us as there is a high chance that our PR patients will end up CR. IMHO 
"NMIBC patients with CIS were previously reported to have a higher incidence of UTUC recurrence than those without it (21.2% vs 2.3%, P < 0.001)24. Schwartz et al. showed that the UTUC recurrence rate was 13% in NMIBC patients with CIS, which was significantly higher than that in those without CIS (3.1%)25. A recent study demonstrated that the smoke load (over 20 pack-year) increased the risk of recurrence and progression (HR = 1.019 and 1.034, P = 0.00004 and 0.00002, respectively) in NMIBC patients treated with BCG, suggesting that the smoke load reduces the efficacy of BCG therapy26. These findings appear to support our results showing that concomitant CIS, but not a history of BCG, is an independent predictor of UTUC recurrence in NMIBC patients with a positive smoking history."
https://www.nature.com/articles/s41598-021-00184-y

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