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Spectral Medical Inc T.EDT

Alternate Symbol(s):  EDTXF

Spectral Medical Inc. is a Canada-based late-stage theragnostic company advancing therapeutic options for sepsis and septic shock. The Company develops and commercializes a treatment for septic shock utilizing its Endotoxin Activity Assay (EAA) diagnostic and the Toraymyxin therapeutic (PMX). PMX is a therapeutic hemoperfusion device that removes endotoxin, which can cause sepsis, from the bloodstream and is guided by the Company’s EAA. PMX is approved for therapeutic use in Japan and Europe and has been used safely and effectively on more than 340,000 patients to date. It has pioneered the development of biochemical markers for the clinical syndrome known as septic shock. It is continuing its legacy business of manufacturing and selling certain proprietary reagents. It develops, produces and markets recombinant proteins, antibodies and calibrators. These materials are sold for use in research and development, as well as in products manufactured by other diagnostic companies.


TSX:EDT - Post by User

Post by SouthernTierTomon Dec 07, 2021 9:28am
101 Views
Post# 34205658

Hmmm...Their Covid19 route is "ONE WAY" too..but NORTH ; - )

Hmmm...Their Covid19 route is "ONE WAY" too..but NORTH ; - )EDT's appears a $outh route with endpoints that may favor a "select group"

It's no wonder "Don" is the go to name for person's "at the wheel"..past and "present" ; - )

Is there a rationale for endotoxin removal in severely ill COVID-19 patients? As a matter of fact, 90% of patients with severe pulmonary forms of COVID-19 have increased endotoxin levels and the level of endotoxin is directly related to the severity of COVID-19. 1,2 Also, these patients are at high risk of sepsis. 3

Endotoxin triggers cytokine storms

The spike protein in SARS-CoV-2 has been shown to bind to endotoxin, starting the inflammatory signalling and dysregulated immune response. 4 Endotoxin is one of the most potent bacterial inducers of cytokines and can induce a cytokine storm through binding to Toll-like receptor 4 (TLR4). 5,6,7,8


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