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Spectral Medical Inc T.EDT

Alternate Symbol(s):  EDTXF

Spectral Medical Inc. is a Canada-based late-stage theragnostic company advancing therapeutic options for sepsis and septic shock. The Company develops and commercializes a treatment for septic shock utilizing its Endotoxin Activity Assay (EAA) diagnostic and the Toraymyxin therapeutic (PMX). PMX is a therapeutic hemoperfusion device that removes endotoxin, which can cause sepsis, from the bloodstream and is guided by the Company’s EAA. PMX is approved for therapeutic use in Japan and Europe and has been used safely and effectively on more than 340,000 patients to date. It has pioneered the development of biochemical markers for the clinical syndrome known as septic shock. It is continuing its legacy business of manufacturing and selling certain proprietary reagents. It develops, produces and markets recombinant proteins, antibodies and calibrators. These materials are sold for use in research and development, as well as in products manufactured by other diagnostic companies.


TSX:EDT - Post by User

Post by mercedesmanon Dec 07, 2021 12:41pm
239 Views
Post# 34206791

The $ 6.4 Billion Question- revisited.

The $ 6.4 Billion Question- revisited.

Perhaps the # 1 most important question...?

Why aren't we talking about the link between Covid and Endotoxemia in the media - thereby letting the investing public know about the potential key that we hold in reducing Covid mortality. The PMX-HP device has been shown to remove endotoxins and it is accompanied by the only FDA approved companion diagnostic (the EAA). And PMX has had over 300,000 safe uses worldwide. 


1) Is there any doubt that our CMO knows this? 
listen from 19m mark for 3 min. to decide for yourself.

https://www.youtube.com/watch?v=GDu8P8_ntuA&t=6s

2) What about the general medical community's understanding?

Well here is just one example.

"Discussion/Conclusion:Elevated EA was observed in a large majority of critically ill patients with COVID-19 and multi-organ dysfunction despite a low incidence of concurrent gram-negative bacteremia. While we observed that elevated EA and nonresponsiveness to EA were associated with AKI in critically ill patients with COVID-19,..."

https://www.karger.com/Article/FullText/518230


3) What about the competion (filters that remove endotoxins) ?

"The spike protein in SARS-CoV-2 has been shown to bind to endotoxin, starting the inflammatory signalling and dysregulated immune response...
Studies show that up to 60% of COVID-19 patients in the ICU have secondary bacterial infections – most commonly respiratory infections from gram-negative bacteria....COVID-19 does not originate from the virus itself but is thought to be released from gram-negative bacteria in the gut, due to inadequate blood flow.  The gut barrier dysfunction that allows endotoxin to leak out from the gut into the blood, can potentially cause sepsis and multiple organ failure."

https://altecomed.com/covid-19/

4) What about the Sepsis Alliance?


"Now that more scientific data are available on COVID-19, the Global Sepsis Alliance can more definitively state that COVID-19 does indeed cause sepsis."

https://www.global-sepsis-alliance.org/news/2020/4/7/update-can-covid-19-cause-sepsis-explaining-the-relationship-between-the-coronavirus-disease-and-sepsis-cvd-novel-coronavirus


*    *    *


So why aren't we talking about this important link to the largest killer of humans in more than a century other than the two world wars -  (5.26 million dead SO FAR ) ?

A Possible answer to the question ?


"Well the is not sufficient scientific evidence yet.  It requires more study !"

To which I respond  "Do all the other hundreds (thousands?) of Nasdaq traded biotech, drug, cancer research companies, etc. remain absolutely mum (silent) about what they HOPE to be able to address/prove in the future via Pre-clinical trials, Phase 1 Trials, Phase 2 trials?, Phase 3 Trials? Or do they articulate what might be possible once more data is avialable and they have gone through a formal FDA approval process?

Do Spectral's competitors and other Biotechs they take every opportunity to tell their story, and attract investors in the meantime, in such a way that will help them to raise future dollars and be able to complete their Trials with a lower cost of capital, while at the same time enhancing shareholder value, thereby attracting more investment dollars, and minimize dilution, as they progress through the various research phases? "

I think we know the answer to that.  

But we don't know why Spectral chooses to remain so quiet about the possibilities, the potential, the hope...during one of the worst periods in history, in terms of human death toll.  

11 million worldwide per annum are dying of Sepsis,  PLUS another 5 million in the past 21 months have died of Covid.  Those numbers do not seem to be declining.

MM
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