Quantum BioPharma Ltd C.QNTM

RE:More publications on this topic which graham failed to menti

[GrahamB]

DavidRosenberg wrote: Inhibitors of protein arginine deiminases and their efficacy in animal models of multiple sclerosis - ScienceDirect

Novel inhibitors of protein arginine deiminase with potential activity in multiple sclerosis animal model - PubMed (nih.gov)

Inhibition of peptidyl-arginine deiminases reverses protein-hypercitrullination and disease in mouse models of multiple sclerosis - PubMed (nih.gov)

Peptidyl Arginine Deiminases and Neurodegenerative Diseases - PubMed (nih.gov)

The important point is to be balanced in presentation of data.

I have heard you say the word “cure” which is completely unsubstantiated.

These are mice models of EAE!

How many humans have been treated?

ZERO.

What data is there these are safe in humans? 
No evidence

The articles you cite are almost a decade ago-here is one for this year -note the discussion of toxicity..
 
“Yet, studies addressing the specificity and toxicity of these inhibitors in cellular systems are limited.In the present study, we sought to address these issues”
 
Applicability of Small-Molecule Inhibitors in the Study of Peptidyl Arginine Deiminase 2 (PAD2) and PAD4
Mara Teresa Martn Monreal1, Alexandra Stripp Rebak2, Laura Massarenti1, Santanu Mondal3, Ladislav enolt4, Niels dum5, Michael L. Nielsen2, Paul R. Thompson3, Claus H. Nielsen1,6*† and Dres Damgaard1
https://doi.org/10.3389/fimmu.2021.716250