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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. It blocks viral entry into host cells while preserving normal immunologic function. The Company is also investigating an intramuscular method of administration of Trogarzo. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy.


TSX:TH - Post by User

Post by scarlet1967on Dec 25, 2021 1:40pm
266 Views
Post# 34262318

Prevalence of High Risk NASH patients

Prevalence of High Risk NASH patients

 

“We estimate at least 2 million adults have high-risk NASH in the US. Moreover, the prevalence of high-risk NASH among individuals with T2DM is higher ranging between 8.7% and 22.5%, supporting the case for coordinated case-finding and management.”

These are patients who can develop severe liver fibrosis, cirrhosis or hepatocellular carcinoma they are also at higher risk of cardiovascular and metabolic diseases as well as extrahepatic malignancies. 

NAFLD is an epidemic disease if not treated will advance to NASH a deadly disease with growing prevalence. There is an urgent need for medical intervention for both conditions.

Due to heterogeneous nature of the conditions world’s well accredited KOLs believe it takes than one drug with specific MOA to treat these diseases.

 

Prevalence of High-risk Non-alcoholic Steatohepatitis (NASH) in the United States: Results from NHANES 2017-2018 - Clinical Gastroenterology and Hepatology

 

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