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Resverlogix Corp T.RVX

Alternate Symbol(s):  RVXCF

Resverlogix Corp. is a Canada-based late-stage biotechnology company. The Company is engaged in epigenetics, with a focus on developing therapies for the benefit of patients with chronic diseases. Its epigenetic therapies are designed to regulate the expression of disease-causing genes. The Company's clinical program is focused on evaluating its lead candidate apabetalone (RVX-208) for the treatment of cardiovascular disease and associated comorbidities, and post-COVID-19 conditions. RVX-208 is a small molecule that is a selective bromodomain and extra-terminal (BET) inhibitor. BET bromodomain inhibition is an epigenetic mechanism that can regulate disease-causing genes. RVX-208 is a BET inhibitor selective for the second bromodomain (BD2) within the BET proteins. It partners with EVERSANA, to support the commercialization of RVX-208 for cardiovascular disease, post-COVID-19 conditions, and pulmonary arterial hypertension in Canada and the United States.


TSX:RVX - Post by User

Comment by narmacon Jan 26, 2022 10:47am
351 Views
Post# 34362144

RE:'IT WILL BE EFFECTIVE' :o()

RE:'IT WILL BE EFFECTIVE' :o(),,,trying to find the statement around the point that Apabetalone reverses the damage to organs etc from Covid 19,,,,so far this is the best I can find,,,

COVID-19 affects not only lung and respiratory tissue but can injure your heart as well. One study, published in the Journal of the American Medical Association, found that 78% of recently recovered COVID-19 patients had evidence of cardiac inflammation.

Now, researchers at QIMR Berghofer Medical Research
Institute, working closely with Resverlogix scientists, believe they may have found a way to prevent this heart damage. The group, led by Professor James Hudson, studied the effects of COVID-19 on cardiac organoids – tiny pieces of tissue that simulate the human heart.

The effort uncovered an important role played by BET proteins in driving the inflammation and cytokine storms that are ultimately responsible for COVID-19 related heart damage. Apabetalone treatment decreased inflammation in the cardiac organoids, reversed the cytokine storm response, reduced viral infection, and prevented tissue damage.

https://www.resverlogix.com/articles-media/featured-stories?story=77.apabetalone-may-prevent-heart-damage-caused-by-covid-19

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