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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Post by Noteableon Feb 13, 2022 1:58pm
308 Views
Post# 34424535

Pressed by Wall Street, Pharma signals openness to M&A

Pressed by Wall Street, Pharma signals openness to M&AFebruary 07, 2022 -  Biopharma Dive

[ Big Pharma ] executives have signaled openness to dealmaking in recent quarterly earnings conference calls. A few have even suggested they may be more active than before.

Expectations are again high that M&A activity will be strong in 2022. Notably, more than a dozen large pharmaceutical companies each will have at least $20 billion in cash available to them by the end of this year, according to analysts at SVB Leerink. Pfizer, in particular, is benefiting hugely from the tens of billions of dollars in revenue generated by its COVID-19 vaccine, while Novartis recently sold a stake in Roche for $21 billion.

A good number of those firms, including Merck, Bristol Myers Squibb, Amgen and AbbVie, face loss of patent exclusivity in the coming years for top-selling drugs like Keytruda, Opdivo, Enbrel and Humira, respectively.

Those factors together should motivate buying as executives hunt for ways to replace expected declines in revenue. 

But they may not prompt large-scale takeovers like past deals for Shire, Celgene and Allergan. "We do not have plans to do larger M&A," said Novartis CEO Vas Narasimhan, adding that "it's harder to make the numbers work to create value for shareholders."  

Instead, many CEOs have expressed greater interest in "bolt-on" deals that can be welded to existing strategies. 

But even bolt-on deals can come with a big sticker price, depending on the size of the acquirer. Merck, which CEO Rob Davis has said will be "appropriately aggressive," bought Acceleron last year for $11.5 billion.



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