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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy. Its portfolio includes Phase I clinical trial of sudocetaxel zendusortide (TH1902), a novel peptide-drug conjugate (PDC), in patients with advanced ovarian cancer.


TSX:TH - Post by User

Post by jeffm34on Feb 24, 2022 12:05pm
174 Views
Post# 34458387

Year end highlights or lowlights

Year end highlights or lowlights Cash on hand $40M

More delays for the NASH program

Trogarzo sales in the US were down $5M (17%) on the year

Hiring spree added about $1.5M/quarter in added operating expense

Cash needed over the next year ~ 120M
56M operating expense (14M x 4) 
64M due from senior notes
Shortfall of $80M this next year

I would expect a financing sometime in the next couple of months based on their immediate cash needs.  Unfortunately the company will not be able to rely on any positive efficacy data from the phase 1 cancer trial to boost the share price before they do another offering.  The trial delays will push any significant efficacy data well into the 2nd half of 2022 and possibly early 2023.  The only question is if there will be a share consolidation to go along with this next offering.  

The only short term catalysts before an offering are possibly a Chinese partnership and the release of more pre clinical data.   

The NASH program has been a disaster for the company.  They wasted 2+ years going after a phase 3 trial for NASH in the general population.  Now they are going back to the FDA to get a phase 2b trial approved.  We had someone here screaming at the top of their lungs that it was a mistake to go that route.  Surely the company had others telling them the same thing.  Instead they push forward with their own plan because they think they know better than everyone else.  

It's hard to find any positives from the update today











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